BDBM50127632 Acetic acid 5-biphenyl-4-ylmethylene-3-aza-tricyclo[4.4.2.0*3,8*]dodec-7-ylmethyl ester::CHEMBL59609

SMILES CC(=O)OCC1C2CCC3CN2C\C(=C/c2ccc(cc2)-c2ccccc2)C1CC3

InChI Key InChIKey=KUMJBZOBGCDDHP-BUVRLJJBSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127632   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127632(Acetic acid 5-biphenyl-4-ylmethylene-3-aza-tricycl...)
Affinity DataKi:  46nMAssay Description:Ability to inhibit [3H]5-HT reuptake at serotonin transporter from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127632(Acetic acid 5-biphenyl-4-ylmethylene-3-aza-tricycl...)
Affinity DataKi:  57nMAssay Description:Ability to inhibit [3H]NE reuptake at norepinephrine transporter from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50127632(Acetic acid 5-biphenyl-4-ylmethylene-3-aza-tricycl...)
Affinity DataKi:  165nMAssay Description:Ability to inhibit [3H]DA reuptake at dopamine transporter from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed