BDBM50127946 3-(2-{2-Oxo-3-[(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-ylmethyl)-amino]-2H-pyridin-1-yl}-acetylamino)-3-(S)-pyridin-3-yl-propionic acid::CHEMBL300494

SMILES OC(=O)C[C@H](NC(=O)Cn1cccc(NCc2ccc3CCCNc3n2)c1=O)c1cccnc1

InChI Key InChIKey=CDIQJJMJTFHODD-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127946   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127946(3-(2-{2-Oxo-3-[(5,6,7,8-tetrahydro-[1,8]naphthyrid...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against human alpha V beta3 receptor using SPAV3 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50127946(3-(2-{2-Oxo-3-[(5,6,7,8-tetrahydro-[1,8]naphthyrid...)
Affinity DataIC50: >3.00E+3nMAssay Description:Ability to bind to the Alpha 2 Beta 3 integrin expressed as inhibitory concentration against ADP-stimulated aggregation of human gel-filtered platele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed