BDBM50128046 (E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6-yloxy)-N-methylbut-2-en-1-aminium::Allyl-{4-[3-(4-bromo-phenyl)-benzo[d]isoxazol-6-yloxy]-but-2-enyl}-methyl-amine::CHEMBL65601::N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6-yloxy)-N-methylbut-2-en-1-aminium

SMILES CN(CC=C)C\C=C\COc1ccc2c(noc2c1)-c1ccc(Br)cc1

InChI Key InChIKey=URARQFSGUNLECM-SNAWJCMRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128046   

TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128046((E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128046((E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6...)
Affinity DataIC50:  28.8nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128046((E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6...)
Affinity DataIC50:  29nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128046((E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed