BDBM50128048 (4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl}-methanone::(6-(4-(4-bromobenzoyl)-3-fluorophenoxy)hexyl)-N-methylcyclopropanaminium::CHEMBL292514::N-(6-(4-(4-bromobenzoyl)-3-fluorophenoxy)hexyl)-N-methylcyclopropanaminium

SMILES CN(CCCCCCOc1ccc(C(=O)c2ccc(Br)cc2)c(F)c1)C1CC1

InChI Key InChIKey=WVHKFNAMXDIZSR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128048   

TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128048((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128048((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  97.7nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128048((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  98nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128048((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  98nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed