BDBM50128057 CHEMBL262532::N-(6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)hexyl)-N-methylcyclopropanaminium::{4-[6-(Cyclopropyl-methyl-amino)-hexyloxy]-piperidin-1-yl}-(4-fluoro-phenyl)-methanone

SMILES CN(CCCCCCOC1CCN(CC1)C(=O)c1ccc(F)cc1)C1CC1

InChI Key InChIKey=WJFVTGWPUVSMHU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128057   

TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128057(CHEMBL262532 | N-(6-(1-(4-fluorobenzoyl)piperidin-...)
Affinity DataIC50:  760nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128057(CHEMBL262532 | N-(6-(1-(4-fluorobenzoyl)piperidin-...)
Affinity DataIC50:  47.9nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128057(CHEMBL262532 | N-(6-(1-(4-fluorobenzoyl)piperidin-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Casmedchem Laboratory

Curated by ChEMBL
LigandPNGBDBM50128057(CHEMBL262532 | N-(6-(1-(4-fluorobenzoyl)piperidin-...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed