BDBM50128059 CHEMBL66359::N-allyl-6-(1-(4-fluorobenzoyl)piperidin-4-yloxy)-N-methylhexan-1-aminium::{4-[6-(Allyl-methyl-amino)-hexyloxy]-piperidin-1-yl}-(4-fluoro-phenyl)-methanone

SMILES CN(CCCCCCOC1CCN(CC1)C(=O)c1ccc(F)cc1)CC=C

InChI Key InChIKey=WNSWHJDIWSRBGI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128059   

TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128059(CHEMBL66359 | N-allyl-6-(1-(4-fluorobenzoyl)piperi...)
Affinity DataIC50:  71nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128059(CHEMBL66359 | N-allyl-6-(1-(4-fluorobenzoyl)piperi...)
Affinity DataIC50:  70.8nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128059(CHEMBL66359 | N-allyl-6-(1-(4-fluorobenzoyl)piperi...)
Affinity DataIC50:  71nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128059(CHEMBL66359 | N-allyl-6-(1-(4-fluorobenzoyl)piperi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed