BDBM50128902 CHEMBL59342::Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hydroxy-2-isobutyrylamino-octadec-4-enyl ester

SMILES CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](COC(=O)NCc1ccncc1)NC(=O)C(C)C

InChI Key InChIKey=XTWYADQOIICZPU-WKKBHVDPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128902   

TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50128902(CHEMBL59342 | Pyridin-4-ylmethyl-carbamic acid (E)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)TBA
LigandPNGBDBM50128902(CHEMBL59342 | Pyridin-4-ylmethyl-carbamic acid (E)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed