BDBM50129428 CHEMBL302374::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-iodo-benzamide::Quinoxaline-1-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide

SMILES Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)cc3)CC2)c1Cl

InChI Key InChIKey=UKOYDIULRIOVQF-UHFFFAOYSA-N

Data  10 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50129428   

TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of rat Dopamine D3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards rat Dopamine receptor D3 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]-IABN as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity for human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  39.3nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  39.3nMAssay Description:Binding affinity for human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  51.4nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  87.5nMAssay Description:Inhibition of [125I]IABN binding to rat Dopamine D2L receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataKi:  88nMAssay Description:Binding affinity towards rat Dopamine receptor D2 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]-IABN as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataIC50:  31.7nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataEC50:  32nMAssay Description:Agonistic activity of quinpirole stimulation of mitogenesis in human Dopamine receptor D3 transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50129428(CHEMBL302374 | N-{4-[4-(2,3-Dichloro-phenyl)-piper...)
Affinity DataIC50:  55.4nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed