BDBM50130065 (R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-(3-trifluoromethyl-phenyl)-ethyl]-3-phenyl-2-phenylmethanesulfonylamino-propionamide::(R)-N-[1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-(3-trifluoromethyl-phenyl)-ethyl]-3-phenyl-2-phenylmethanesulfonylamino-propionamide::CHEMBL309394

SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1cccc(c1)C(F)(F)F)NC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)Cc1ccccc1)C(=O)c1nccs1

InChI Key InChIKey=LXTUIXZKXFFKAT-YTCPBCGMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130065   

TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  8.49E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  8.49E+4nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed