BDBM50130170 (S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propan-2-ol::(endo)-1-(1H-Indol-4-yloxy)-3-[3-(4-methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propan-2-ol::(exo)-1-(1H-Indol-4-yloxy)-3-[3-(4-methoxy-benzo[b]thiophen-2-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propan-2-ol::CHEMBL421328

SMILES COc1cccc2sc(cc12)[C@H]1C[C@@H]2CC[C@H](C1)N2C[C@H](O)COc1cccc2[nH]ccc12

InChI Key InChIKey=KABCJYIMLUDARM-HAGHYFMRSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130170   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  0.170nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  0.170nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 1A receptor by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  1.30nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  16nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 1A receptor by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130170((S)-1-(1H-Indol-4-yloxy)-3-[(1R,3S,5S)-3-(4-methox...)
Affinity DataKi:  19nMAssay Description:Inhibition of 5-HT induced [35S]-GTP-gammaS, binding at human cloned 5-HT 1A receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed