BDBM50131055 3,4-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL86022

SMILES COc1ccc2nc3-c4[nH]c5ccccc5c4CCn3c(=O)c2c1OC

InChI Key InChIKey=GOTQXTBYAQVBOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131055   

TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131055(3,4-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131055(3,4-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  140nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131055(3,4-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  870nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed