BDBM50131352 3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmethyl)-7,8-dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole::CHEMBL93801

SMILES COc1cc2OCC3C(CN4CCN(Cc5csc6ccccc56)CC4)ON=C3c2cc1OC

InChI Key InChIKey=SNKCREOVGWDJDI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131352   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131352(3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmet...)
Affinity DataKi:  7.20nMAssay Description:In vitro binding affinity towards rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131352(3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmet...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity towards human adrenergic alpha-2C adrenergic receptor using [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131352(3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmet...)
Affinity DataKi:  66nMAssay Description:In vitro binding affinity towards human alpha-2A adrenergic receptor using [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131352(3-(4-Benzo[b]thiophen-3-ylmethyl-piperazin-1-ylmet...)
Affinity DataKi:  370nMAssay Description:In vitro binding affinity towards rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed