BDBM50131358 3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c]isoxazol-3-ylmethyl)-piperazin-1-yl]-1-phenyl-propan-1-one::CHEMBL328735

SMILES COc1cc2OCC3C(CN4CCN(CCC(=O)c5ccccc5)CC4)ON=C3c2cc1OC

InChI Key InChIKey=AWPNMWRTPSQMFC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131358   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131358(3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c...)
Affinity DataKi:  5.30nMAssay Description:In vitro binding affinity towards human adrenergic alpha-2C adrenergic receptor using [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131358(3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c...)
Affinity DataKi:  12nMAssay Description:In vitro binding affinity towards human alpha-2A adrenergic receptor using [3H]-rauwolscineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131358(3-[4-(7,8-Dimethoxy-3a,4-dihydro-3H-chromeno[4,3-c...)
Affinity DataKi:  123nMAssay Description:In vitro binding affinity towards rat serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed