BDBM50131814 CHEMBL3634598

SMILES Cc1cc2oc(=O)n(CCC(O)=O)c2cc1Cl

InChI Key InChIKey=QPMPFAMMRAXUAV-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131814   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50:  13nMAssay Description:Inhibition of kynurenine monooxygenase (unknown origin) by MS rapidfire assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length human GST-tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using kynurenine as substrate measured aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50131814(CHEMBL3634598)
Affinity DataIC50:  631nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using kynurenine as substrate measured after 20 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed