BDBM50131968 CHEMBL127828::Thiophene-3-carboxylic acid {2-[5-(2-fluoro-phenyl)-1-methyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-2-yl]-ethyl}-amide

SMILES CN1C(CCNC(=O)c2ccsc2)CN=C(c2ccccc2F)c2ccccc12

InChI Key InChIKey=AVUSYTRJVKZPGP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131968   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity against opioid receptor kappa 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity determined against Opioid receptor kappa 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity of compound was determined against Opioid receptor mu 1 from native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  3nMAssay Description:Binding affinity determined against Opioid receptor mu 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  15nMAssay Description:Binding affinity of compound was determined against Opioid receptor delta 1 from a native receptor in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131968(CHEMBL127828 | Thiophene-3-carboxylic acid {2-[5-(...)
Affinity DataKi:  69nMAssay Description:Binding affinity determined against Opioid receptor delta 1 from human cloned receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed