BDBM50132441 3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)-2-oxoindoline-5-sulfonamido)propanamide::3-{3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonylamino}-propionamide::CHEMBL105427

SMILES COc1ccc2n(C)cc(\C=C3/C(=O)Nc4ccc(cc34)S(=O)(=O)NCCC(N)=O)c2c1

InChI Key InChIKey=FMAJMCVSAGAPDM-NVMNQCDNSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132441   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50132441(3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)...)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50132441(3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132441(3-(3-((5-methoxy-1-methyl-1H-indol-3-yl)methylene)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed