BDBM50132445 3-[1-(5-Methoxy-1H-indol-3-yl)-meth-(Z)-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid amide::CHEMBL106226
SMILES COc1ccc2[nH]cc(\C=C3/C(=O)Nc4ccc(cc34)S(N)(=O)=O)c2c1
InChI Key InChIKey=SDSZFWFNRRXLGU-UUASQNMZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50132445
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against human Syk protein tyrosine kinase expressed in yeast Klyveromyces lactisMore data for this Ligand-Target Pair
TargetLow affinity immunoglobulin epsilon Fc receptor(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Effect on IgE/Fcepsilon RI triggered rat basophil cell (RBL-2H3) degranulation assessed by measuring the amount of 5-HT releaseMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Inhibition of TrkC (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of TrkA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of TrkB (unknown origin)More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
University Of Tartu
Curated by ChEMBL
University Of Tartu
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of GAL4 fused TrkA (unknown origin) expressed in PC12 cells transfected with pFA2-Elk plasmid and pFR-luciferase plasmid measured for 18 h...More data for this Ligand-Target Pair