BDBM50132490 CHEMBL3633928
SMILES NC(=O)Nc1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
InChI Key InChIKey=HUROJPARIBKVDY-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50132490
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibitory activity against metabotropic glutamate receptor 5 (mGluR5)More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human EGFR expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 186nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) expressed in mouse BaF/3 cells assessed as cell growth inhibition after 72 hrs by MTS assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Korea University Of Science And Technology (Ust)
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of His-tagged human recombinant Her2 (676 to 1255 residues) expressed in baculovirus by fluorescence based assayMore data for this Ligand-Target Pair