BDBM50132684 CHEMBL331799::Methyl-(3-naphthalen-2-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine

SMILES CNCC1C2CCC(C2)C1c1ccc2ccccc2c1

InChI Key InChIKey=PORDAYLSLHLTRQ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132684   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataKi:  25nMAssay Description:In vitro inhibition of DA re-uptake into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataKi:  266nMAssay Description:Displacement of [3H]-Nisoxetine from norepinephrin transpoterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataIC50:  50nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataIC50:  45nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132684(CHEMBL331799 | Methyl-(3-naphthalen-2-yl-bicyclo[2...)
Affinity DataIC50:  87nMAssay Description:In vitro inhibition of DA re-uptake into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed