BDBM50132688 CHEMBL323447::Dimethyl-(3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-ylmethyl)-amine

SMILES CN(C)CC1C2CCC(C2)C1c1cccc2ccccc12

InChI Key InChIKey=OGDCBGGLUZRVAG-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132688   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataKi:  183nMAssay Description:Displacement of [3H]-citalopram from Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataKi:  430nMAssay Description:Displacement of [3H]-WIN-35,428 from Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataIC50:  93nMAssay Description:In vitro ability of compound to inhibit 5-HT re-uptake of radiolabelled [3H]-tritium trasmitter into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataIC50:  1.51E+3nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132688(CHEMBL323447 | Dimethyl-(3-naphthalen-1-yl-bicyclo...)
Affinity DataIC50:  297nMAssay Description:In vitro inhibition of [3H]-NE re-uptake into synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed