BDBM50132877 2-{3-Fluoro-2-[(4-{[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetylamino]-methyl}-phenylamino)-methyl]-phenoxy}-5-methoxy-benzoic acid::CHEMBL432438

SMILES COc1ccc(Oc2cccc(F)c2CNc2ccc(CNC(=O)CO[C@@H]3C[C@H](C)CC[C@H]3C(C)C)cc2)c(c1)C(O)=O

InChI Key InChIKey=QCBLTCFSOCTHJG-XJUCSQNASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132877   

TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50132877(2-{3-Fluoro-2-[(4-{[2-((1R,2S,5R)-2-isopropyl-5-me...)
Affinity DataIC50:  1.40E+3nMAssay Description:Plasminogen Activator Inhibitor-1 (PAI-1) activity was determined by inhibition of Urokinase-type plasminogen activator using primary assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed