BDBM50133050 CHEMBL385696::Opioid Peptide [d-Ala(8)]Dynorphin derivative

SMILES CC(C)C[C@H](NC(=O)[C@]1(CCc2ccccc2C1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=OFTCNSAONABMAO-YXFRXOEWSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133050   

TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133050(CHEMBL385696 | Opioid Peptide [d-Ala(8)]Dynorphin ...)
Affinity DataKi:  0.890nMAssay Description:Binding affinity of the compound towards rat Opioid receptor kappa 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]-dipren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133050(CHEMBL385696 | Opioid Peptide [d-Ala(8)]Dynorphin ...)
Affinity DataKi:  32.9nMAssay Description:Binding affinity towards rat Opioid receptor mu 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]-DAMGOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133050(CHEMBL385696 | Opioid Peptide [d-Ala(8)]Dynorphin ...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound towards mouse Opioid receptor delta 1 expressed in CHO cells of chinese hamster ovary was determined using [3H]-DPDG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50133050(CHEMBL385696 | Opioid Peptide [d-Ala(8)]Dynorphin ...)
Affinity DataEC50:  72.4nMAssay Description:Inhibition of Forskolin-Stimulated Adenylyl Cyclase in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed