BDBM50133077 (S)-4,4-Dimethyl-2-((R)-3-phenyl-2-phenylmethanesulfonylamino-propionylamino)-pentanoic acid [(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-amide::CHEMBL422974

SMILES CC(C)(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nccs1

InChI Key InChIKey=UKTWXNRRUKGLCW-NXCFDTQHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133077   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133077((S)-4,4-Dimethyl-2-((R)-3-phenyl-2-phenylmethanesu...)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133077((S)-4,4-Dimethyl-2-((R)-3-phenyl-2-phenylmethanesu...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133077((S)-4,4-Dimethyl-2-((R)-3-phenyl-2-phenylmethanesu...)
Affinity DataIC50:  440nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed