BDBM50133095 CHEMBL130592::N-{1-[4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-naphthalen-2-yl-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide

SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)Cc1ccccc1)C(=O)c1nccs1

InChI Key InChIKey=SBXVXUCQXQAMRZ-XFCANUNOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133095   

TargetProthrombin(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133095(CHEMBL130592 | N-{1-[4-Guanidino-1-(thiazole-2-car...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133095(CHEMBL130592 | N-{1-[4-Guanidino-1-(thiazole-2-car...)
Affinity DataIC50:  770nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50133095(CHEMBL130592 | N-{1-[4-Guanidino-1-(thiazole-2-car...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed