BDBM50133229 1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL133868

SMILES CC(N)Cc1c[nH]c2ccc3OCCCc3c12

InChI Key InChIKey=VVHJUSGIUWQPIT-UHFFFAOYSA-N

Data  16 KI  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133229   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133229(1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-...)
Affinity DataIC50:  1.09E+4nMAssay Description:In vitro inhibitory concentration required against [3H]8-OH-DPAT binding to cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133229(1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration required against Alpha-2A adrenergic receptor using [3H]clonidine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133229(1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-...)
Affinity DataIC50:  0.700nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133229(1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration required against Alpha-2C adrenergic receptor using [3H]clonidine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed