BDBM50133332 CHEMBL3183233
SMILES COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1
InChI Key InChIKey=TWJGQZBSEMDPQP-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50133332
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged human MALT1 (catalytic domain-339-719 aa) by fluorescence based assay using 25 uM Ac-LRSR-AMC as substrateMore data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of full length recombinant wild type MALT1 (unknown origin) using Ac-LVSR-AMC as substrate by HTS assayMore data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Institute Of Basic Science (Ibs)
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...More data for this Ligand-Target Pair