BDBM50133824 4-(3-Cyano-pyridin-2-yl)-piperazine-1-carboxylic acid (4-isopropyl-phenyl)-amide::CHEMBL121092
SMILES CC(C)c1ccc(NC(=O)N2CCN(CC2)c2ncccc2C#N)cc1
InChI Key InChIKey=HEIOPGPLZVQXDP-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50133824
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: >2.50E+4nMAssay Description:Vanilloid receptor subtype 1 antagonist activity based on its ability to block low pH-induced activation of the rat VR1 channel in a HEK293 cell lineMore data for this Ligand-Target Pair
TargetPantothenate kinase 3(Homo sapiens (Human))
St. Jude Children'S Research Hospital
Curated by ChEMBL
St. Jude Children'S Research Hospital
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant N-terminal His6-fusion tagged PanK3 expressed in Escherichia coli BL21 (DE3) measured after 10 mins in presence of AT...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Purdue Pharma
Curated by ChEMBL
Purdue Pharma
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:Vanilloid receptor subtype 1 antagonist activity based on its ability to block capsaicin-induced (CAP) activation of the rat VR1 channel in a HEK293 ...More data for this Ligand-Target Pair