BDBM50134036 2-(2,3-Dimethyl-phenylamino)-benzoic acid::2-(2,3-Dimethyl-phenylamino)-benzoic acid(Mefenamic acid)::2-(2,3-dimethylphenylamino)benzoic acid::CHEMBL686::CI-473::CN-35355::INF-3355::MEFENAMIC ACID::Ponstel::cid_4044::mefanamic acid

SMILES Cc1cccc(Nc2ccccc2C(O)=O)c1C

InChI Key InChIKey=HYYBABOKPJLUIN-UHFFFAOYSA-N

Data  9 KI  21 IC50  4 EC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134036   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50:  560nMAssay Description:Inhibition of AKR1C3 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50:  6.97E+3nMAssay Description:Inhibition of AKR1C2 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50:  3.91E+3nMAssay Description:Inhibition of AKR1C1 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of AKR1C4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50134036(2-(2,3-Dimethyl-phenylamino)-benzoic acid | 2-(2,3...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of COX1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed