BDBM50134241 CHEMBL3746642

SMILES CC(Cn1c(C)ncc1[N+]([O-])=O)OC(=O)c1ccc(cc1)C1CC(=NN1C(C)=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=HZKRIAYPKCGAPE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134241   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134241(CHEMBL3746642)
Affinity DataIC50:  3.53E+3nMAssay Description:Inhibition of His-tagged human HER-2 cytoplasmic domain (676-1245 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134241(CHEMBL3746642)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50134241(CHEMBL3746642)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of His-tagged EGFR cytoplasmic domain (645-1186 aa) (unknown origin) assessed as inhibition of autophosphorylation by TR-fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed