BDBM50134320 CHEMBL3746293

SMILES CN1CCn2nc(Nc3cc(n[nH]c3=O)-c3ccc(F)c(NC(=O)c4cc5ccccc5s4)c3C)cc2C1

InChI Key InChIKey=MZSDTUIZKGUVHK-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50134320   

TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  14nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  230nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of FGR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  3nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  924nMAssay Description:Inhibition of Src (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50:  91nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50134320(CHEMBL3746293)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed