BDBM50134404 (R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid [4-(3-oxo-morpholin-4-yl)-phenyl]-amide::(S)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid [4-(3-oxo-morpholin-4-yl)-phenyl]-amide::CHEMBL122023

SMILES CCC[C@@H](NC(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(cc1)N1CCOCC1=O

InChI Key InChIKey=TWXYXCQOGPSRAK-LJQANCHMSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50134404   

TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity of the compound against human Coagulation factor X in a purified enzyme systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50:  5.60nMAssay Description:Binding affinity of the compoumd to human coagulation factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity of the compoumd against human trypsin was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human trypsin activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against human thrombin activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory concentration against human serine protease factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50134404((R)-2-[3-(4-Chloro-phenyl)-ureido]-pentanoic acid ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against human thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed