BDBM50134461 2-(3-Hydroxy-4-methoxy-phenyl)-5,6,7-trimethoxy-chromen-4-one::CHEMBL124885::eupatorin-5-methylether

SMILES COc1ccc(cc1O)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1

InChI Key InChIKey=LYLDPYNWDVVPIQ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134461   

TargetCytochrome P450 1A1(Homo sapiens (Human))
University Of Crete

Curated by ChEMBL
LigandPNGBDBM50134461(2-(3-Hydroxy-4-methoxy-phenyl)-5,6,7-trimethoxy-ch...)
Affinity DataKi:  630nMAssay Description:Inhibition of CYP1A1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Crete

Curated by ChEMBL
LigandPNGBDBM50134461(2-(3-Hydroxy-4-methoxy-phenyl)-5,6,7-trimethoxy-ch...)
Affinity DataKi:  670nMAssay Description:Inhibition of CYP1B1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50134461(2-(3-Hydroxy-4-methoxy-phenyl)-5,6,7-trimethoxy-ch...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration that cause a 50% inhibition in tubulin assembly as measured by an increase inturbidity using microtubule assembly assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed