BDBM50135139 6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL147828

SMILES CN(Cc1cnc2nc(N)nc(N)c2c1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=BVOBMRMQGLHNQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135139   

TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135139(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50:  131nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135139(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50:  110nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135139(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-py...)
Affinity DataIC50:  180nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed