BDBM50135143 6-[(3-Methoxy-phenylamino)-methyl]-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL356279

SMILES COc1cccc(NCc2cnc3nc(N)nc(N)c3c2)c1

InChI Key InChIKey=HGIQAONNGREZAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135143   

TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135143(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[2,3-d]py...)
Affinity DataIC50:  790nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135143(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[2,3-d]py...)
Affinity DataIC50:  520nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135143(6-[(3-Methoxy-phenylamino)-methyl]-pyrido[2,3-d]py...)
Affinity DataIC50:  210nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed