BDBM50135162 CHEMBL147705::Sulfamic acid 2-adamantan-1-yl-4-oxo-4H-chromen-6-yl ester

SMILES NS(=O)(=O)Oc1ccc2oc(cc(=O)c2c1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=JREFEGGQRUQPSO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135162   

TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institute For Biomedical Research Vienna

Curated by ChEMBL
LigandPNGBDBM50135162(CHEMBL147705 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataKi:  190nMAssay Description:Inhibitory activity against human steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institute For Biomedical Research Vienna

Curated by ChEMBL
LigandPNGBDBM50135162(CHEMBL147705 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institute For Biomedical Research Vienna

Curated by ChEMBL
LigandPNGBDBM50135162(CHEMBL147705 | Sulfamic acid 2-adamantan-1-yl-4-ox...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against human steroid sulfatase over-expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed