BDBM50135947 2-(2-Methylaminomethyl-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-methanesulfonyl-biphenyl-4-yl)-amide::CHEMBL147171

SMILES CNCc1ccccc1-n1nc(cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=UYYJSSZRKZXYHL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135947   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135947(2-(2-Methylaminomethyl-phenyl)-5-trifluoromethyl-2...)
Affinity DataKi:  28nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135947(2-(2-Methylaminomethyl-phenyl)-5-trifluoromethyl-2...)
Affinity DataKi: >2.50E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135947(2-(2-Methylaminomethyl-phenyl)-5-trifluoromethyl-2...)
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed