BDBM50136250 (1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydroxyamide 2-{[4-(quinolin-4-yloxymethyl)-phenyl]-amide}::CHEMBL135696

SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(COc2ccnc3ccccc23)cc1

InChI Key InChIKey=CTQQHSLVVFZJEY-OALUTQOASA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50136250   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of matrix metalloproteinase-9(MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibitory activity of the compound against matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataIC50:  8nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136250((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataIC50:  8nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed