BDBM50136259 (2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid 3-hydroxyamide 2-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide}::(2S,3S)-N3-hydroxy-1-methyl-N2-(4-((2-methylquinolin-4-yl)methoxy)phenyl)piperidine-2,3-dicarboxamide::CHEMBL134908::IM-491

SMILES CN1CCC[C@@H]([C@H]1C(=O)Nc1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=RJSKOAOWDAMMHR-GMAHTHKFSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50136259   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibitory activity of the compound against matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataIC50:  6.20nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataIC50:  6nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid ...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed