BDBM50136471 (S)-1-{2-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid methylamide::CHEMBL441095
SMILES CNC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3ccc(cc3)C(N)=O)OCCc2c1
InChI Key InChIKey=PNTVCCRNJOGKGA-QFIPXVFZSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50136471
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in Chinese hamster ovary cells (CHO cells)More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to human 5-HT1D expressed in CHO cells assessed as inhibition constant incubated for 1 hr by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Beijing Normal University
Curated by ChEMBL
Beijing Normal University
Curated by ChEMBL
Affinity DataKi: >1.80E+4nMAssay Description:Binding affinity to 5-HT2B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair