BDBM50136597 3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl)-benzamide::CHEMBL336234

SMILES C[C@H]1CN(CCc2ccccc2)CC[C@@]1(C)c1cccc(c1)C(N)=O

InChI Key InChIKey=KWKRFFSOCHKOSI-HTAPYJJXSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136597   

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  4.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  72nMAssay Description:Concentration required to inhibit the binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataKi:  95nMAssay Description:Binding affinity at cloned human kappa opioid receptor by [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50136597(3-((3R,4R)-3,4-Dimethyl-1-phenethyl-piperidin-4-yl...)
Affinity DataIC50:  1.90nMAssay Description:Concentration required to inhibit agonist (loperamide) stimulated [35S]GTP-gamma-S, binding to membranes containing the cloned human mu opioid recept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed