BDBM50136768 CHEMBL442315::Peptide analogue::Somatostatin analogue::Somatostatin-28

SMILES CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)C(N)C(C)=C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H]1CSSC[C@@H](NC(=O)[C@@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCCCN)NC1=O)[C@@H](C)O)[C@@H](C)O)C(O)=O

InChI Key InChIKey=XOPQWKKOVYFZNR-XNPSXLOZSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50136768   

TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.20nMAssay Description:Binding affinity towards human somatostatin receptor type 1 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity towards human somatostatin receptor type 5 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  2.5nMAssay Description:Binding affinity towards human somatostatin receptor type 4 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.5nMAssay Description:Binding affinity towards human somatostatin receptor type 3 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.30nMAssay Description:Binding affinity towards human Somatostatin receptor type 2 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.80nMAssay Description:Binding affinity towards human Somatostatin receptor type 4 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  7.10nMAssay Description:Binding affinity towards human Somatostatin receptor type 3 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.90nMAssay Description:Binding affinity towards human Somatostatin receptor type 1 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  3.90nMAssay Description:Binding affinity towards human Somatostatin receptor type 5 using 125I-[Leu,DTrp,Tyr]SRIF-28 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Salk Institute

Curated by ChEMBL
LigandPNGBDBM50136768(CHEMBL442315 | Peptide analogue | Somatostatin ana...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity towards human somatostatin receptor type 2 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed