BDBM50137283 6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide::6-Benzyloxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide::CHEMBL358539

SMILES COc1ccc(cc1)S(=O)(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NO

InChI Key InChIKey=OVUDWXYTKUKYAX-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50137283   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  34nMAssay Description:Inhibition of matrix metalloproteinase-14 (MMP-14)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  30nMAssay Description:Inhibition of matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  2.42E+3nMAssay Description:Inhibition of matrix metalloproteinase-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  88nMAssay Description:Inhibition of matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  22nMAssay Description:Inhibition of matrix metalloproteinase-16 (MMP-16)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of matrix metalloproteinase-12 (MMP-12)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  744nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of matrix metalloproteinase-15 (MMP-15)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed