BDBM50137552 5-[(1R,3S)-3-(3,5-Dichloro-phenyl)-2,2-dimethyl-cyclopropyl]-4-methyl-1H-imidazol-2-ylamine::CHEMBL51950
SMILES Cc1nc(N)[nH]c1[C@@H]1[C@@H](c2cc(Cl)cc(Cl)c2)C1(C)C
InChI Key InChIKey=OHEXEGZWGZINIT-NEPJUHHUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50137552
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of sodium dependent recovery of pH following imposed acidosis in AP1 cell line expressing the human NHE-1 isoform.More data for this Ligand-Target Pair