BDBM50138135 CHEMBL3754762
SMILES Nc1ncc(cc1-c1ccc(Cl)cc1)-c1ccc(=O)[nH]c1
InChI Key InChIKey=ZBWLRCRQGFYVCE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50138135
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MAP4K4 transfected in 293 MSR cells assessed as inhibition of phosphorylation of traf2 at ser/thr residue by ELISAMore data for this Ligand-Target Pair