BDBM50138640 3-(4-Chloro-phenyl)-2-[3-(4-chloro-phenyl)-isoxazol-5-yl]-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL103223

SMILES CN1C2CCC1C(C(C2)c1ccc(Cl)cc1)c1cc(no1)-c1ccc(Cl)cc1

InChI Key InChIKey=WHFIJZLIDVACTG-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138640   

TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138640(3-(4-Chloro-phenyl)-2-[3-(4-chloro-phenyl)-isoxazo...)
Affinity DataKi:  3.79E+3nMAssay Description:Binding affinity towards norepinephrine transporter was determined using [3H]nisoxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138640(3-(4-Chloro-phenyl)-2-[3-(4-chloro-phenyl)-isoxazo...)
Affinity DataIC50: >7.60E+4nMAssay Description:Inhibitory concentration required to inhibit serotonin transporter 5-HTT was determined by using [3H]paroxetine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138640(3-(4-Chloro-phenyl)-2-[3-(4-chloro-phenyl)-isoxazo...)
Affinity DataIC50:  5.29E+3nMAssay Description:Inhibition of norepinephrine transporter (NET) determined using [3H]nisoxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138640(3-(4-Chloro-phenyl)-2-[3-(4-chloro-phenyl)-isoxazo...)
Affinity DataIC50:  6.42nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed