BDBM50138645 2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane::CHEMBL322856

SMILES COc1ccc(cc1)-c1cc(on1)C1C2CCC(CC1c1ccc(C)cc1)N2C

InChI Key InChIKey=WDCUMSARTHPFTE-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50138645   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138645(2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-...)
Affinity DataKi:  366nMAssay Description:Binding affinity towards serotonin transporter 5-HTT was determined using [3H]paroxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138645(2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-...)
Affinity DataKi:  455nMAssay Description:Binding affinity towards norepinephrine transporter was determined using [3H]nisoxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138645(2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-...)
Affinity DataIC50:  3.93nMAssay Description:Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138645(2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-...)
Affinity DataIC50:  4.03E+3nMAssay Description:Inhibitory concentration required to inhibit serotonin transporter 5-HTT was determined by using [3H]paroxetine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50138645(2-[3-(4-Methoxy-phenyl)-isoxazol-5-yl]-8-methyl-3-...)
Affinity DataIC50:  756nMAssay Description:Inhibition of norepinephrine transporter (NET) determined using [3H]nisoxetine radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed