BDBM50139028 (R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-dimethylaminomethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide::1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid {(R)-1-(4-chloro-benzyl)-2-[4-(2-dimethylaminomethyl-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-amide::CHEMBL349850
SMILES CN(C)Cc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1
InChI Key InChIKey=VJWZUOKQCXSJRH-FQLXRVMXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50139028
Affinity DataKi: 60nMAssay Description:Agonistic potency towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Binding affinity towards human Melanocortin 5 receptor (MC5R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (MC3R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (MC1R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Agonistic potency of the compound towards human Melanocortin 3 receptor (MC3R) was determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Effective concentration against cAMP release in CHO cells expressing human melanocortin-4 receptorMore data for this Ligand-Target Pair