BDBM50139577 4-(5-{[3-(3-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile::CHEMBL434879

SMILES Clc1cccc(CN2CCc3ccccc3C(NCc3cncn3Cc3ccc(cc3)C#N)C2=O)c1

InChI Key InChIKey=JUHFBGZNDZFVMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50139577   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50139577(4-(5-{[3-(3-Chloro-benzyl)-2-oxo-2,3,4,5-tetrahydr...)
Affinity DataIC50:  23nMAssay Description:Inhibition of farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed