BDBM50139614 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-ethylpicolinamide::4-{4-[3-(4-Chloro-3-trifluoromethyl-phenyl)-ureido]-phenoxy}-pyridine-2-carboxylic acid ethylamide::CHEMBL350129

SMILES CCNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1

InChI Key InChIKey=YENKTYRMOJFDJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139614   

TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  26nMAssay Description:Inhibition of B-Raf1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50139614(4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against human Raf-1 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed