BDBM50140206 CHEMBL3753623

SMILES COc1ccc(cn1)-c1ccc(OC(F)(F)F)c(NC(=O)Nc2ccncc2)c1

InChI Key InChIKey=RPXILCAORZPTRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50140206   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50140206(CHEMBL3753623)
Affinity DataIC50:  100nMAssay Description:Inhibition of FGFR1 (unknown origin) incubated for 1 hr assessed as luminescence changes using ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50140206(CHEMBL3753623)
Affinity DataIC50: >500nMAssay Description:Inhibition of KDR (unknown origin) incubated for 1 hr assessed as luminescence changes using ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The First Affiliated Hospital Of Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50140206(CHEMBL3753623)
Affinity DataIC50:  103nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr assessed as luminescence changes using ATP by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed